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Cytokines May Diagnose Prostatitis
Dr. Jeffrey Stern, MD, et al. presented at the 2005 AUA Annual Meeting that two cytokines might be useful for diagnosing prostatitis.
The two cytokines are macrophage inflammatory protein 1-alpha (MIP-1alpha) and monocyte chemoattractant protein-1 (MCP-1).
Both cytokines were found to be elevated in the expressed prostatic secretions (EPS) of patients with chronic pelvic pain syndrome compared to controls.
The cytokines were elevated in noninflammatory as well as inflammatory CPPS.
Inflammatory CPPS is NIH category IIIa, while noninflammatory CPPS is NIH category IIIb.
Dr. Stern is currently the chief urology resident at Northwestern University Medical Center in Chicago.
Prostatitis can raise the PSA level. Only by better determing what effect prostatitis has on the PSA, and how to treat prostatitis, will we be able to better diagnose prostate cancer.
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