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PCa Support Forum

Prostate Cancer Prevention Trial

   In theory, the drug Proscar (finasteride) might prevent prostate cancer. There is a study underway to determine this. The study is called the "Prostate Cancer Prevention Trial." In the study: 18,000 healthy men have been randomized to take either finasteride or a placebo.

Finasteride produces hormone deprivation to the prostate by lowering the amount of DHT (dihydrotestosterone) that can be formed in the prostate. The National Cancer Institute is behind this large study of volunteers to see if 5 mg/day of Proscar can prevent the formation of prostate cancer in men over a 10-year period. The study will reach its endpoint in 2004.

Update:

This study has been completed and has resulted in confusion rather than an answer. There were less cases of prostate cancer in the men treated with finasteride but there were also more cases of aggressive prostate cancer. Now, if you look at the medical literature, there are many studies written to try and figure out if finasteride does more good than harm.

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